The CCIC first came together in the spring of 2000 as a result of initial funding from the CIHR under the leadership of Dr Mary Lynch. Since that time the CCIC has grown to include basic science and clinical researchers and other health care practitioners. The CCIC has been consulted for Senate committee reports, regulatory guidelines for medical marijuana and CCIC members have conducted and published research on cannabinoids.

In June 2007 the CCIC became a federally incorporated non-profit organization to continue to further our understanding of cannabinoids. The need for educational initiatives has also become clear and the CCIC aims also to provide a credible source of information on cannabinoids for the public and health care practitioners.